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Sources

Irinotecan Drug Labeling

  • https://www.pharmgkb.org/label/PA166104831

Irinotecan Toxicity (dose decrease not supported)

  • http://ascopubs.org/doi/abs/10.1200/JCO.2005.05.5400

Irinotecan Dosing

  • http://ascopubs.org/doi/full/10.1200/jco.2014.55.2307
  • https://www.researchgate.net/publication/263397222_Dose-Finding_and_Pharmacokinetic_Study_to_Optimize_the_Dosing_of_Irinotecan_According_to_the_UGT1A1_Genotype_of_Patients_With_Cancer

5-FU

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831181/

Fluorouracil Drug Label

  • https://www.pharmgkb.org/label/PA166104807
  • https://www.ncbi.nlm.nih.gov/pubmed/17015056

Paclitaxel

  • https://academic.oup.com/annonc/article/24/6/1472/179298/CYP2C8-3-increases-risk-of-neuropathy-in-breast

Economic Impact Taxanes/Capecitabine

  • http://www.ahdbonline.com/issues/2012/august-2012-vol-5-no-5-special-issue-asco-2012-payers-perspective/1079-article-1079

Capecitabine

  • https://www.pharmgkb.org/guideline/PA166109594
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831181

Methotrexate

  • https://www.fredhutch.org/en/news/releases/2001/06/MTHFR.html
  • http://www.ascopost.com/issues/may-1-2014-supplement/methotrexate-and-fluorouracil-toxicities-a-collaborative-practice-approach-to-prevention-and-treatment
  • http://www.bloodjournal.org/content/bloodjournal/98/1/231.full.pdf?sso-checked=true

Economics

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312207
  • http://ar.iiarjournals.org/content/34/10/5241.full

 

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