Sources
Irinotecan Drug Labeling
Irinotecan Toxicity (dose decrease not supported)
Irinotecan Dosing
- http://ascopubs.org/doi/full/10.1200/jco.2014.55.2307
- https://www.researchgate.net/publication/263397222_Dose-Finding_and_Pharmacokinetic_Study_to_Optimize_the_Dosing_of_Irinotecan_According_to_the_UGT1A1_Genotype_of_Patients_With_Cancer
5-FU
Fluorouracil Drug Label
Paclitaxel
Economic Impact Taxanes/Capecitabine
Capecitabine
Methotrexate
- https://www.fredhutch.org/en/news/releases/2001/06/MTHFR.html
- http://www.ascopost.com/issues/may-1-2014-supplement/methotrexate-and-fluorouracil-toxicities-a-collaborative-practice-approach-to-prevention-and-treatment
- http://www.bloodjournal.org/content/bloodjournal/98/1/231.full.pdf?sso-checked=true
Economics
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312207
- http://ar.iiarjournals.org/content/34/10/5241.full